Scientific advisory board

Prof. Dr. Tanja de Gruijl, PhD

Prof. de Gruijl advises DCPrime on questions related to the current R&D activities, and to immune-monitoring. She heads the DC research group and tumour immuno-monitoring unit of the Division of Immunotherapy of the Department of Medical Oncology at VUmc in Amsterdam, and has more than 15 years of  track record in translational immunology. Prof. de Gruijl performed the original research that led to the discovery that the normal functions of DC from human blood can be mimicked by certain cell lines. Her main line of research is the in vivo modulation of DC subsets for tumour immunotherapeutic purposes, through targeted adenovirus-mediated gene transfer and local cytokine administration.

Prof. Dr. Walter Urba, MD, PhD

Prof. Urba is Director of the Providence Cancer Center and cancer research for the Earle A. Chiles Research Institute in Portland, OR. He has a long track record in groundbreaking immunotherapy research, acting as principal investigator on local, national and international trials of cytokines, antibodies and cancer vaccines. His team in Portland developed OX40 agonists as immunotherapy for cancer, a strategy that is being developed by MedImmune. He has been an advisor to the immunotherapists of the VUmc for many years, and now advises DCPrime as well. Prof. Urba is past chair of the FDA Cellular, Tissue and Gene Therapy Advisory Committee and served on the National Cancer Institute’s Board of Scientific Counselors for Clinical Services and Epidemiology. He has (co)authored more than 200 publications.

Prof. Dr. Pedro Romero, MD

Prof. Romero was educated as an MD in Colombia, and performed his research training at New York University medical school before joining the LICR. Prof. Romero is a specialist in peptide-based immunotherapy and has made numerous contributions to the field of cancer immunology. He holds a number of patents and has (co)authored published over 160 papers.

Prof. Dr. Sjoerd van der Burg, PhD

Prof. van der Burg is a professor in experimental cancer immunology and therapy at the department of clinical oncology of the Leiden University Medical Center, he received his Ph.D. in Immunology from the University of Leiden, the Netherlands. His research interest is in tumour immunopathology with an emphasis on the local immune response, T-helper cells, regulatory T cells and cytotoxic T cells in tumour immunity, as well as in immunotherapy of cancer, in particular the development of therapeutic vaccine strategies and the adoptive transfer of ex-vivo expanded T cells. He has extensive experience with the monitoring of human T cell responses and exploits this to guide the development of therapeutic vaccines against cancer.

Prof. Dr. Rik J Scheper, MD, PhD, Co-founder of DCPrime

Prof. Scheper is an immunologist and experimental pathologist in the Department of Pathology of VUmc in Amsterdam. In close collaborations with several clinical departments, Prof. Scheper leads research groups in the fields of multidrug resistance, tumour-immunology and immuno-dermatology, all at the VUmc. Prof. Scheper was awarded many national and international grants to support his research, and worked closely with a number of companies, including Boehringer Ingelheim, Eurocetus, Numico, Organon Teknika, Intracell, Coley Pharmaceutical Group, Medarex, Kirin Breweries and Solvay. As (co-)inventor, he contributed in collaborations with industry to the development of several patents. He also is the CEO-CSO of VUmc spin-off company A-Skin, a tissue engineering company.

Last updated: augustus 16, 2016